Chiefs vs. Broncos Score Prediction: Bo Nix Gets His 'Welcome to Arrowhead' Moment

The Chiefs host the Broncos on Sunday hoping to start a new winning streak in this AFC West rivalry. Denver beat Kansas City in late October in 2023, snapping a 16-game losing streak in the matchup.

Now, rookie QB Bo Nix and head coach Sean Payton have the Broncos at 5-4 competing for a playoff spot. Patrick Mahomes and the Chiefs are suddenly entertaining a possible undefeated season, coming off their best offensive performance of the season in a 30-24 overtime win against the Buccaneers.

Denver got blown out 41-10 by Baltimore last week, putting extra importance on this game. If Kansas City stays focused, another blowout could be in order. Let's lock down a score prediction for this 12:00 PM CST Week 10 tilt.

Chiefs vs. Broncos Score Prediction

Prior to the Ravens' demolition, the Broncos were widely considered to have one of the NFL's best defenses. Patrick Surtain is on the short list of the league's top cornerbacks and Denver had only surrendered more than 18 points once prior to Week 9.

Lamar Jackson and Derrick Henry exposed some holes that Mahomes will exploit. The Chiefs now have 14 straight wins including the postseason. With each passing week, they're getting closer to history. This will be Nix's first time facing Steve Spagnuolo and respectfully, it's hard to imagine him finding much success.

Denver ranks 25th in yards per play (5.0). While the defense is second in opponent yards per play (4.7), it faltered in a massive way last week. The Broncos have losses to the Seahawks, Steelers, Chargers, and Ravens. Seattle isn't in the playoffs but they're competing for a spot, while every other team would be in the postseason.

The Broncos' reputation has been bolstered by cupcake opponents like the Panthers, Saints, Raiders, and Jets. When they face a step up in competition, things fall apart. The Chiefs are obviously a very large step.

It's worth noting that games between these teams are relatively close. Kansas City is just 1-4 against the spread in the last five meetings. FanDuel Sportsbook has the Chiefs as 7.5-point favorites with a total set at 41.5, implying a low-scoring contest but one in which Mahomes prevails.

Mahomes and Spagnuolo aren't losing to a rookie signal caller, especially considering how embarrassing losing to the Broncos was in 2023. After a mediocre defensive performance against the Bucs, Spagnuolo will have his group ready to hunt.

Expect smooth sailing for the Chiefs as Nix gets his "Welcome to Arrowhead" moment.

Score Prediction: Chiefs 24 - Broncos 13

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Odds refresh periodically and are subject to change.